True or False: High-output fistula (>500 mL/day) is an indication for PN.

True or False: High-output fistula (>500 mL/day) is an indication for PN.

• A. False
• B. True
• C. Only with infection
• D. Not defined

Answer: (B)

High-output fistula causes substantial ongoing losses of fluids, electrolytes, and protein. These losses rapidly deplete body stores and impede healing, so nutrition must compensate beyond what the enteral route can reliably provide. When fistula output is high (commonly defined around 500 mL/day or more) or enteral feeding cannot meet metabolic needs or be tolerated, parenteral nutrition is indicated to maintain energy balance and support healing. Enteral nutrition is preferred when feasible, but in high-output fistulas the amount that can be delivered enterally is often insufficient, making PN the appropriate choice to ensure adequate nutrition.

High-output fistula causes substantial ongoing losses of fluids, electrolytes, and protein. These losses rapidly deplete body stores and impede healing, so nutrition must compensate beyond what the enteral route can reliably provide. When fistula output is high (commonly defined around 500 mL/day or more) or enteral feeding cannot meet metabolic needs or be tolerated, parenteral nutrition is indicated to maintain energy balance and support healing. Enteral nutrition is preferred when feasible, but in high-output fistulas the amount that can be delivered enterally is often insufficient, making PN the appropriate choice to ensure adequate nutrition.