How do zinc levels typically change in systemic inflammatory response syndrome (SIRS)?

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Multiple Choice

How do zinc levels typically change in systemic inflammatory response syndrome (SIRS)?

Explanation:
During systemic inflammatory response, zinc is pulled from the bloodstream into tissues such as the liver as part of the acute-phase response. Inflammatory cytokines, especially IL-6, stimulate hepatic metallothionein, which binds zinc and sequesters it away from plasma. This causes circulating zinc levels to fall, a condition known as hypozincemia, which is commonly seen in SIRS. As inflammation resolves, zinc may return toward normal. So the typical change is a decrease in zinc levels.

During systemic inflammatory response, zinc is pulled from the bloodstream into tissues such as the liver as part of the acute-phase response. Inflammatory cytokines, especially IL-6, stimulate hepatic metallothionein, which binds zinc and sequesters it away from plasma. This causes circulating zinc levels to fall, a condition known as hypozincemia, which is commonly seen in SIRS. As inflammation resolves, zinc may return toward normal. So the typical change is a decrease in zinc levels.

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